ABSTRACT

Alport’s syndrome is a hereditary disease characterized by progressive nephritis, sensorineural hearing loss and ocular abnormalities. A 36 years-old man was applied to ophthalmology department with a complaint of decreased visual acuity in both eyes. His history included deafness and renal disease since childhood. On ocular examination, the best corrected Snellen visual acuity was 1/10 in both eyes. Slitlamp biomicroscopic examination revealed anterior and posterior lenticonus in both eyes. Retinal flecks a spare of bilateral perimacular areas were detected on fundoscopy. On systemic examination, sensorineural hearing loss was detected by audiometry. He had developed end-stage renal failure which required hemodialysis for three years. The patient was diagnosed with Alport’s syndrome on the basis of clinical history and examination. The patient had clear lens phacoemulsification with implantation of triple–piece acrylic hydrophobic intraocular lens (IOL) was implanted in both eyes one week apart. A one year postoperatively, the patient had the best corrected Snellen visual acuity of 10/10 in both eyes, with myopic correction and IOL was well centered in the bag. Clear lens phacoemulsification is a safe and effective surgical procedure for the treatment of anterior and posterior lenticonus in patients with Alport’s syndrome, allowing for rapid visual rehabilitation.