ABSTRACT
Conclusion:
In idiopathic ERM patients central macular function may be monitored by PHP. Especially in idiopathic ERM patients having low visual acuity a prominent visual field defect was detected by PHP
Results:
Fifteen eyes of 12 patients with a mean age of 63.9±7.4 years and a mean visual acuity of 0.7±0.2 were recruited in the study. Mean central macular thickness was found to be 334.4±72.1 by OCT. In hyperacutiy deviation map, significant visual field defect was detec-ted in 9 eyes whereas it was entirely normal in 6 eyes. When the eyes with and without visual field defect were compared, we found a statistically significant difference in mean visual acuity (p=0.005 Mann-Whitney U test); however there was no statistically significant difference in mean central macular thickness measured by OCT (p= 0.689 Mann-Whitney U test).
Materials and Methods:
Patients diagnosed to have idiopathic ERM were enrolled in the study. After a detailed ophthalmological examination, all participants were evaluated by optical coherence tomography (OCT). Central 14°x14° visual field was tested by PHP (Foresee PHP, Notalvision); hyperacuity deviation map and hyperacuity defect maps were recorded. Pa-tients having high false positive or false negative ratios were excluded.
Purpose:
To assess central macular function by preferential hyperacuity perimetry (PHP) in patients with idiopathic epiretinal membrane (ERM).
Keywords:
Idiopathic epiretinal membrane, preferential hyperacuity perimetry (PHP), optical coherence tomography (OCT)
References
1Mitchell P, Smith W, Chey T, Wang J J, Chang A. Prevalence and association of epiretinal membranes. The Blue Mountains Eye Study. Austral Ophthalmol 1997;104:1033-40.
2Hirokawa H, Jalkh AE, Takahas hi M, Takahashi M,Trempe CL, Schepens CL. Role of the vitreous in idiopathic preretinal macular fibrosis. Am J Ophthalmol 1988;106:536-545.
3Wise GN. Clinical features of idiopathic preretinal macular fibrosis. Schoenberg Lecture. Am J Ophthalmol 1975;79:349-347.
4Preferential Hyperacuity Perimetry Study Group. Preferential hyperacuity perimeter (Preview PHP) for detecting choroidal neovascularization study. Ophthalmology 2005; 112:1758-1765.
5Loewenstein A, Malach R, Goldstein M, Leibovitch I, Barak A, Baruch E, Alster Y, Rafaeli O, Avni I, Yassur Y. Replacing the amsler grid: a new method for monitoring patients with age-related macular degeneration. Ophthalmology 2003;110:966-970.
6Tanikawa A, Horiguchi M, Kondo M, Suzuki S, Terasaki H, Miyake H. Abnormal focal macular electroretinograms in eyes with idiopathic epimacular membrane. Am J Ophthalmol 1999;127:559-64.
7Saito Y, Hirata Y, Hayashi A, Fujikado T, O hji M, Tano Y. The vis ual performance and metamorphopsia of patients with macular holes. Arch Ophthalmol 2000;118:41-46.
8Bouwens MD, van Meurs JC. Sine Amsler charts:a new method for the follow-up of metamorphopsia in patients undergoing macular pucker surgery. Graefes Arch Clin Exp Ophthalmol 2003;241:89-93.
9Richter-Mueksch S, Vécsei-Marlovits PV, Sacu SG, Kiss CG, Weinges sel B, Schmidt-Erfurth U. Functional macular mapping in patients with vitreomacular pathologic features before and after surgery. Am J Ophthalmol. 2007;144:23-31.
10Goldstein M, Loewenstein A, Barak A, Pollack A, Buckelman A, Katz H, Springer A, Schachat AP, Bresssler NM, Bressler SB, Cooney MJ, Alster Y, Rafaeli O, Malach R; Preferential Hyperacuity Perimeter Research Group. Results of a multicenter clinical trial to evaluate the preferential hyperacuity perimeter for detection of age-related macular degeneration. Retina 2005;25:296-303.
11Westheimer G. The spatial sense of the eye. Invest Ophthalmol Vis Sci 1979;18:893-912.
12Enoch JM, Williams RA, Es sock EA, Barricks M. Hyperacuity perimetry: assessment of macular function through ocular opacities. Arch Ophthalmol 1984;102:1164-1168.
13Preferential Hyperacuity Perimeter (PHP) Research Group. Results of a multi-center clinical trial to evaluate the preferential hyperacuity perimeter for detection of age-related macular degeneration. Retina 2005;25:296-303.
14Mc Donald HR, Verre WP, Aaberg TM. Surgical Management of idiopathic epiretinal membranes. Ophthalmology 1986;978-983.
15Shinoda K, Ishida S, Kawashima S, Matsuzaki T, Y amada K, Katsura H. A new method for quantification of metamorphopsia in patients with epiretinal membrane. Jpn J Ophthalmol 2000;44:424-427.
16Akar S, Arvas S, Kızılkaya M, Özkan Ş. Makula önü membranların cerrahi tedavi sonuçları. Türk Oftalmoloji Gazetesi 2002;32:256-265.
17Öztürkmen C, Eldem B, Kadayıfçılar S. Epiretinal membranlarda klinik özellikler, izlem ve cerrahi sonuçları. Türk Oftalmoloji Gazetesi 2003;33:34-38.
18Moschos M, Apostolopoulos M, Ladas J, Theodossiadis P, Malias J, Moschos M, Papaspirou A, Theodossiadis G. Assessment of macular function by multifocal electroretinogram before and after epimacular membrane surgery. Retina 2001;21:590-595.
19Oh KT, Boldt HC, Maturi RK, Folk JC, Kardon RH. Evaluation of patients with visual field defects following macular hole surgery using multifocal electroretinography. Retina 2000;20:238-243.
20Varano M, Tedes chi M. Disorders of the vitreoretinal interface clinics. Chapter 4.8. In Perimetry and the fundus: an introduction to microperimetry. Midena E. USA. SLACK Incorporated. 2007,133-143.
21Rohrschneider K, Springer C, Blültmann S, Völcker HE. Microperimetry-comparison between the Micro Perimeter 1 and scanning laser ophthalmoscope-fundus perimetry. Am J Ophthalmol 2005;139:125-134.
22Sidd RJ, Fine SL, Owens SL, Patz A. Idiopathic preretinal gliosis. Am J Ophthalmol 1982;94:44-48.
23Appian AP, Hirose T. S econdary causes of premacular fibrosis. Ophthalmology 1989;96:389-392.
24Kamei M, Hisatomi T, Ishibashi T, Tano Y. Epiretinal Membranes. Chapter 16. In Retinal imaging. Huang D, Peter KK, Careen YL, Elias IT. China. MOSBY Elsevier. 2006,191-197.